LPD-824

LPD-824
Clinical data
Other names	LPD-824, N-Pyrrolidyl-lysergamide
Routes of; administration	Oral
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Renal
Identifiers
	IUPAC name (8β)-6-Methyl-8-(pyrrolidin-1-ylcarbonyl)-9,10-didehydroergoline;
CAS Number	2385-87-7 ;
PubChem CID	200628;
ChemSpider	173678 ;
ChEMBL	ChEMBL302524 ;
CompTox Dashboard (EPA)	DTXSID20946653 ;
Chemical and physical data
Formula	C20H23N3O
Molar mass	321.424 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N1CCCC1)[C@@H]4C=C3c5cccc2c5c(c[nH]2)C[C@H]3N(C4)C;
	InChI InChI=1S/C20H23N3O/c1-22-12-14(20(24)23-7-2-3-8-23)9-16-15-5-4-6-17-19(15)13(11-21-17)10-18(16)22/h4-6,9,11,14,18,21H,2-3,7-8,10,12H2,1H3/t14-,18-/m1/s1 ; Key:SETDYMMXQQXCRP-RDTXWAMCSA-N ;
	(verify)

N-Pyrrolidyllysergamide (LPD-824), also known as lysergic acid pyrrolidide, is a derivative of ergine. It is reported to be a serotonin receptor antagonist^[1] and have some mild, short lasting LSD-like effects at a dose of 800 micrograms.^[2]

References

^ Dunn WJ, Bederka JP (February 1974). "The role of hydrophobicity in the antiserotonin activity of LSD analogs". Research Communications in Chemical Pathology and Pharmacology. 7 (2): 275–85. PMID 4818374.
^ "Erowid Online Books : "TIHKAL" - #26 LSD-25".

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[Dunn_1974-1] Dunn WJ, Bederka JP (February 1974). "The role of hydrophobicity in the antiserotonin activity of LSD analogs". Research Communications in Chemical Pathology and Pharmacology. 7 (2): 275–85. PMID 4818374.

[2] "Erowid Online Books : "TIHKAL" - #26 LSD-25".

[1]

[2]

LPD-824

See also

References

zproxy.org

Clinical data

Other names	LPD-824, N-Pyrrolidyl-lysergamide
Routes of administration	Oral
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Renal
Identifiers
IUPAC name (8β)-6-Methyl-8-(pyrrolidin-1-ylcarbonyl)-9,10-didehydroergoline
CAS Number	2385-87-7^Y
PubChem CID	200628
ChemSpider	173678^Y
ChEMBL	ChEMBL302524^Y
CompTox Dashboard (EPA)	DTXSID20946653
Chemical and physical data
Formula	C₂₀H₂₃N₃O
Molar mass	321.424 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(N1CCCC1)[C@@H]4C=C3c5cccc2c5c(c[nH]2)C[C@H]3N(C4)C
InChI InChI=1S/C20H23N3O/c1-22-12-14(20(24)23-7-2-3-8-23)9-16-15-5-4-6-17-19(15)13(11-21-17)10-18(16)22/h4-6,9,11,14,18,21H,2-3,7-8,10,12H2,1H3/t14-,18-/m1/s1^Y Key:SETDYMMXQQXCRP-RDTXWAMCSA-N^Y
(verify)